Dave Andrews has written an absolutely wonderful explanation of how to select the right Weber carbs
and how to tune them. You can read it all here: Weber Carb Selection and Tuning
He has also created easy to use software. It is linked below. When you click on the link, you'll get a window asking you if you want to run or save the software. It's your choice. When you do run it, it will open a window that asks for the size of engine you're working with. It also asks at what rpm you make peak power (be realistic), and if you are tuning for power or flexibility. Then it gives you typical settings you can use as a baseline for setting up your carbs. When adjusting my new DCOE 45's, I paid for the assistance of a Weber expert, then put the car on a dyno. Later, I checked our results against Mr. Andrews' recommendations, and found that the little software program was spot on. I don't know if this will work as well for you, but you're welcome to give it a try: Jetting
Cylinder head repair
Reinz warning - also applies to some other head gasket manufacturers
Below is the illustration Alfa Parts sends out with the 2-liter Victor Reinz head gaskets they sell. The drawing is used with the permission of Jon Norman, of Alfa Parts. His number is 1-800-890-2532. I don't know if other engine sizes are at risk; that's a question for Jon.If you don't understand why this diagram could save you time and money, do a search of the Alfa Digest or AlfaBB.com.
The quick version of the story is this: Older 2-liter motors have oil galleys at the back of the block. Newer 2-liter motors don't. Reinz -- and some other gasket manufacturers -- stopped putting sealant around the oil galley holes, probably when the newer motors came out, and now older engines are at risk of oil and coolant mixing if Jon's diagram is not followed when installing these head gaskets.
I know this from first-hand experience and have corresponded with several others who've suffered the same ugly fate. Alfa Parts was the first company I'm aware of that understood the problem and offered help before their customers found out the hard way. Jon's website is: www.alfapartscatalog.com. I understand from Centerline that now they also offer this advice to Reinz purchasers.The sealant referred to in the diagram is Permatex Ultra Grey.